I’ve been a fan of marriedtothesea.com for a while now, but this one deserves special mention.

I’ve been a fan of marriedtothesea.com for a while now, but this one deserves special mention.

Over the past 48 hours I cut through the eastern half of the U.S., half by rail, half by air, accompanied by ‘psychics’, ranch owners, and some guy. It felt absolutely wonderful to sleep in my own bed last night. That said, I’m recalling the train circling around New York City and the man outside Union Station in Washington inquiring about the name of the second toe, the one right next to the big toe, and feel quite glad to have taken the extra excursion after the Society for Neuroscience conference.
More soon.
I’m sitting in the Brain and Cognitive Sciences building at MIT right now, looking over railroad tracks. I picked up a biography of A. J. Ayer at Harvard Square earlier and just finished looking through the photos–oh Freddie. I arrived in Boston last night, by train, from Washington. A grandma sat next to me after leaving Penn Station in NYC, was in the city to collect books for a library she’s making for her grandchildren. What a great idea! A dentist from Boston sat next to me for the remainder of the trip.
I was on the MIT website before leaving Winnipeg and saw a seminar on Nuclear and Particle Physics listed for today. I’ll be attending that as well, but I just discovered that there is a ‘Brain Lunch’ right next to the McGovern Institute for Brain Research, a seminar on modeling and methods for electrophysiologcal data. Seeing as I’ve never been involved in electrophysiology work before, everything will likely be over my head. I will absolutely die if Nancy Kanwisher walks in though *academic crush*.
I do have my digital camera in my pocket and will take some shots of the campus shortly. Interestingly enough, the Gehry building, the crazy one (well, they’re all crazy), is right next door. Too weird seeing it on powerpoint at SFN and now sitting right next to it. A lot of photos of this building coming up too!
**Update**
Well, well, well. Turns out the electrophysiology talk was understandable. The physics talk, not so much. Granted my background in particle physics is only one introductory 4th year course, but this was nuts! The talk was on Quantum Chromodynamics (QCD) and the level of discussion, or rather grilling, was something I had never seen before. So many people at conferences nod their heads and mutter words like ‘of course!’ and ‘yes!’. These guys did too, but you knew they meant it. The lecture was supposedly open to the general public, although it was far from a generalists grasp in physics, let alone a generalist from the public. Still, very interesting to see.
Without further ado, pictures from MIT:
The view from the Brain and Cognitive Sciences Building.
I’m back at the corner of Luckie and Broad, this time across the street, having another coffee and killing time before my train leaves for Washington DC. I met a mother and her daughter when I was waiting for the bus to bring me back downtown. She said she was from Alabama and that they were out here to prepare a few things as they were moving to Atlanta. Then a bee interrupted our conversation. No bees here, it’s to windy, and a little chilly.
I finally met up with Shelley, Jake, and Mr. Evil Monkey on Saturday night.
Sunday is somewhat of a blur to me. Actually, most of the conference is a blur to me. Rows and rows of posters, gadgets, books, bad coffee, and ugly carpet tends to distract. I do recall interviewing Elaine Snell from the Dana Alliance in Europe for my radio show. There some really neat things going on in London, so if you’re in the area, or will be soon, check out the Dana Centre. There are also webcasts of several presentations. A few that look interesting: a panel on science and religion, one on laughter, and another on Thrills, complete with fair grounds on-site! It felt quite official, Elaine snuck me into the Press Room and we had our own booth, it sounds excellent! Again, I’ll update this with the time the interview airs.
Later in the evening I attended the Brain Awareness Social and noticed what were becoming familiar faces. There’s a lot more in public outreach than I realized. There was a comment from the audience about metrics for determining the success of Brain Awareness campaigns. This was said to be a likely focus of the next meeting in San Diego.
In between these two events, I have no recollection of what happened. Let’s just assume I wandered around the poster session.
So, neat posters: I have a friend in Bergen, Norway that I have not seen for a very long time. I didn’t even realize the researcher was from Bergen, but now as I look at this paper I’m taken back to Australia where we met. Anyways, the poster was from the Bergen fMRI Group and was titled ‘Computation of the fractal dimension in patients with schizophrenia using MR images’. This was cool. I had never heard of using fractals in magnetic resonance imaging (MRI) before. Fractals are mathematical rules that create pretty pictures like the Mandelbrot set. The beauty in fractals isn’t simply the images the create though. Fractals can be used for data compression, which has implications for a lot of things, especially now that things are increasingly becoming digital. In this case, fractals were used to study the brain morphometry, the measurement of the shape of regions of the brain, in controls and schizophrenics. Typically, after an MR image has been acquired, a researcher, i.e. their underling, strips the skull from the image using one of a host of algorithms. The shape of the brain can then be characterized and volumes for the entire brain or specific regions of interest can be determined. Now, what’s typically done is the shape is defined in Euclidean space. Using fractals, the guys out in Bergen were able to detect differences in the shape of control and schizophrenic brains. It’s not the whole answer, but it might be another tool to help in characterizing structural differences for brains in healthy and disease states.
Alright, so I am in another place yet again, this time a European bakery, ducking the cold wind outside and still waiting for my train. By the time I post this I will likely be in Washington.
I’m under an overcast sky on the corner of Broad and Luckie in Atlanta, drinking coffee and sitting. Finally sitting. It seems pleasant enough to write here as pigeons swirl around the intersection and cute university girls pass by.
To reminisce:
I attended the Frank Gehry talk last Saturday. I went to the Neuroethics Symposium shortly thereafter and was quite impressed with the lineup of speakers. When all was said and done, there was a lot less talk about philosophy than I had thought would be the case, save for one incident in which an attendee spoke up during the question period only to call Colin Blakemore naive for saying that his approach to ethics has been from a reductionist perspective. To some extent I understand where the attendee was coming from, at least in considering the whole person in ethical matters, but I’m quite positive Blakemore would have talked more to this effect if time constraints weren’t operating. This was not the time to voice such concerns, let alone call names. More constructively, a philosopher stood up and asked what role philosophers might play in neuroethics. The answer was a call for dialogue between philosophers, bioethicists, scientists, physicians, etc, and while this is a basic statement, is still quite important to have such a statement brought forward.
Judy Illes from Stanford gave the first talk. Opening with a review of beta blockers and a vignette illustrating a traveller passing through a security checkpoint at an airport and unfortunately remarking ‘this is where you get your brain scanned’, Illes reiterated Howard Gardner’s hope for neuroeducators with research experience and pedagogical training to engage the public in an informed dialogue about the implications of neuroscience. The linear process of research moving from researchers to the media and finally to the public was discussed and the replacement of such a linear process with a circular one was hoped for. In fact, shifts in the way the application and consequences of neuroscience proceeds seems to have been a major theme of the conference. From the presidential lectures to these talks on neuroethics, an engagement of clinical observation as a means to inform basic research and an engagement of the public to inform neuroethics kept popping up.
Back to the talk, Illes discussed the profound effect false-positives and small-n research can have on patients and their families when such studies are taken to heart. At the end, Illes called for large-scale, longitudinal, multi-modal studies, clear clinical goals, and an examination of the consequences of neuroscience, both positive (say, neuroimaging as a means of mitigating stigma for certain disorders) and negative (small-n studies that need further follow up before something definitive can be said).
Gladys Maestre, a research clinician from Maracaibo, Venezuela gave the next talk. I won’t go too much into the details now as the rain has forced me into the Atlanta Public Library and I’m starting to think about having dinner soon. I will say that I had the pleasure of interviewing Dr. Maestre for my radio show on CKUW and will update my blog with the date the interview will air as soon as I know myself.
It might just be more informative if I post this blurb from the meeting planner:
Even in its young life, neuroethics has established itself firmly in the history of neuroscience. Much of the early activity has been driven by the intersection of neuroscience and biomedical ethics in the United States, but a significant emphasis is now visible worldwide in both developed and developing countries. The specific objectives of this symposium are to explore the landscape of activity in neuroethics on an international scale, the ethical, legal and social impact of neuroethics across country and cultural boundaries, and strategies for expanding neuroethics activity worldwide.
To achieve our goals we will draw on a number of themes. In regenerative medicine, for example, where does therapy stop and enhancement start? Will this technology give rise to a cognitive divide between those with and without access and a declining tolerance of those on the tails of the cognitive bell curve? In seeking ways in which neuroscience can better improve brain health in developing countries such as Venezuela, imperatives include establishing clear priorities, strengthening the capacity of local institutions, and meeting health needs. But, as many of the translational approaches of neuroscience involve sophisticated technology, will neuroscience unintentionally contribute to the “science divide” between rich and poor countries? In Japan, government efforts to promote research in the development and maintenance of brain function are focused on both ends of the life spectrum. The drive to improve function is pressing in this culture, but an overriding ethical issue is that no one yet knows what an optimal brain should be. Nurturing core neural functions while respecting individual differences is a vast challenge. In mental health research in the UK for example, and on a global scale, the interplay of genetics, development and environment poses yet other challenges. Knowledge of the origins of pathology have the potential to lead to early intervention and treatment decisions, but advances also raise concerns about poor uses of risk data and the medicalisation of human traits. How can neuroethics, neuroscientists and sponsors of research best foster debate and wise decision-making? Overall, how can the academic community and the public both become better engaged with neuroscience? Drawing on an emerging Canadian model, we will call for a paradigm shift that embraces the early and proactive inclusion of all types of experts - neuroscientists and geneticists, ethicists, philosophers and others - in the research process.
Three cheers for the Canadian model!
The pangs are hitting me and there’s an interesting book called ‘Design 1935-1965: What Modern Was’ lying next to me. I think I’ll read this for a bit and then fill my belly and haul the offical SFN murse around a little more.
The conference is officially over and I finally have time to digest the copious amounts of acronyms and graphs that have been impinging on my eyes over the past week. Beyond the poster sessions, there were a few other things that caught my eye.
Centennial Park and the Leukemia and Lymphoma Society’s Light the Night campaign.

A Brazilian bakery for birthday cake purposes and late-night sandwiches.

The area where my hotel is in is largely hispanic, with most of the signs in Spanish. I did my laundry last night and the owner could not speak English. Her son, not more than 8 years old, had to translate for her. Needless to say the area differs a bit from the CNN Center. I like it out here.

And of course random smattering of odd SFN postering during the last minutes of the conference.


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I have to really update this. Too much has happened over the past 4 days here in Atlanta. I shall try to in my down time should I decide to play hookey and visit the aquarium with some Calgarians. In the interim though, I just received an email from a very good friend of mine. She’s playing a part in a film directed by another friend that has been selected for the Calgary and Toronto film festivals! If you’re in the Calgary or the Toronto regions, check this out. Looks like it will screen in Toronto for the After Dark Film Festival this coming Sunday (October 22). Congratulations Rany and Candace!
I figured it was time to write this, although I will be travelling back in time slightly.
Friday, October 13
Neurobiology of Disease: So, my alarm didn’t work. Surprisingly I was still up by 8 AM. This didn’t cut it for making it to the workshop on time, however. After figuring out the MARTA system I arrived late and walked in just as an ALS patient was describing her condition. Unfortunately I missed the patient with SMA. The overall tone of the workshop was technical and given my background is heavily weighted to neuroimaging, all the signaling pathways tended to go over my head.
I was particularly bad and started to put the finishing touches on my NSERC application during the workshop. The plan was to dine and dash during the lunch and get everything finished, but the arrangement of the tables were so pretty and we had the chance to sit with lecturers who were running mini-talks after the lunch, so I headed to the table with Dr. Jeremy Shefner from New York and Dr. Martin Turner from Oxford.
Both Dr. Shefner and Martin lead the discussion wonderfully and although the emphasis was on the physiology of ALS, there was some neuroimaging. I mentioned people (read: superiors whose projects I’m quite removed from) at my lab are working on DTI of the spinal cord. This looks to be a very interesting field, and as Dr. Martin mentioned, a biomarker for ALS is need. DTI could be the answer. It might just be, as these things tend to go, that an accident in the lab yields something to this effect, much like the current drug Rilutek was discovered when some floor cleaner was walloped and contaminated a chemical sample lying on the bench.
Naturally I asked Dr. Martin about Oxford. He said Worcester College is beautiful and that I should go even if the Rhodes drops away. Damnit! Why do you have to be so inspiring and yet so debt-inducing!
I skipped out on the second talk and reception to finish my NSERC application for graduate neuroscience. Unfortunately the Kinkos/FedEx was closed by the time I wrapped things up. I sent the package the following morning, but it will only be arriving in Ottawa Monday morning, a day after the deadline. I’m hoping the online application is counted as meeting the deadline, while the paper is just a required hard copy. But it can’t help my application. Regardless, thanks to Dr. Martin I don’t care as much if the application doesn’t go through. Oh what a tangled web we weave.
Saturday, October 14
The day started off late. I had made plans to meet Shelley by the giant peach, but phone problems and rail connections promptly snuffed that plan out. I spent a lot of time wandering around, staring aimlessly at the massive crowds. Frank Gehry’s talk was the first lecture of the day that I attended. The thing is, I’m a fan of architecture discussions, provided it isn’t too post-modern, and although Gehry’s work is weird, I kind of like it. So, whatever came out of the man’s mouth, I was going to enjoy it. I had seen snippets of the documentary on Frank Gehry before leaving Winnipeg, so it felt somewhat homely walking in the massive B1 Exhibit hall and seeing the documentary being played on massive screens. Somewhat. Gehry went through his buildings, giving the audience a photo tour of his work and the process that gets him there. I was taken aback though at the lack of neuroscience in the talk. There was tremendous opportunity to touch on perception, on acoustics, on geometry, and the only major questions coming from the audience and Rusty Gage were about creativity.
I headed to the International symposium on Neuroethics after Gehry’s talk. After being squeezed through the doors of B1 like a sardine, of course. The attendance at the symposium was a lot lower than I had expected, but I found it fascinating nonetheless.
More to come, but I must prepare to present my poster tomorrow and get ready for the Faculty for Undergraduate Neuroscience Social.
And sleep. Yes, that too.
It’s done. Rhodes application, check. Commonwealth application, check. UCAS application, check. NSERC application, check. Poster not lost yet, check. I can now finally relax and enjoy the conference. I’d like to post about the Neurobiology of Disease workshop I participated in this morning but it looks like one last early morning for me. More tomorrow.
and now i sit here and relax before writing again.
I made it. After running around the university this morning, after signing papers and getting letters to department heads, after finding out that the notary public of the University of Winnipeg was snowed in, after some incredibly amazing guy heard my conversation at the Collegiate and made some phone calls to find me a replacement, after saying goodbye at the research council, after arriving late at the airport, I made it.
Funny. Customs said that my Canadian passport didn’t have to be valid, that it still proved my citizenship. Not ha-ha Funny. But funny.
I’ve already met another conference attendee. He left Winnipeg as well and we bumped into each other while waiting to board the flight to Atlanta. This was somewhat ha ha funny. He pulled out his itinerary and my poster was listed as one to check out.
I’ve also noticed that going to a conference makes me keenly aware of anyone else carrying a poster or tubelike container on an airplane.
I did some thinking on the plane and believe I have a reasonable research proposal to put forth for NSERC. No, I did not manage to finish up the paperwork back home. I will likely have to duck out of the Neurobiology of Disease class tomorrow to send off the package. Why do you require a paper copy submitted before the deadline when you organize everything with online applications, NSERC? Why?
There have been a few observations that have taken the cortisol kick out of this trip. One. Strange voices in American airports. Minneapolis/St. Paul has a British voice advising you watch your step by the human conveyer belt. British? Atlanta’s airport literally has the men’s sinks sing whenever you pass your hand under the infrared motion detector. Something to the effect of ‘Oh what a beautiful day’.
I also met a girl on the bus from the east coast who’s in town for a massage conference. I wasn’t sure if this was code, but she seemed pleasant enough. Maybe a little too pleasant? No. I don’t think so. Oh oh. She sat next to a woman wearing a 2 Pac shirt who was reading ‘Baby Doll: she was robbin’ the rich to feed the poor’, complete with hot pink dust jacket and ‘Baby Got Back’ accents on the cover model.
Now back to the resesarch proposal.